Abstract

If you need to reduce the number of curve points to those only showing a significant slope change:

sbReducePoints

Literature

If this simple slope change approach is not successful, use the (external link!) Ramer–Douglas–Peucker algorithm.

Appendix sbReducePoints Code

Please read my Disclaimer.

Option Explicit

Function sbReducePoints(rX As Range, rY As Range, _
    Optional dMaxSlopeDelta As Double = 0.001) As Variant
'sbReducePoints eliminates points from a given set
'in case the slopes between these points do not differ
'too much.
'Source (EN): http://www.sulprobil.de/sbreducepoints_en/
'Source (DE): http://www.berndplumhoff.de/sbreducepoints_de/
'(C) (P) by Bernd Plumhoff 29-Mar-2023 PB V0.1

Dim bNewSlope               As Boolean

Dim dSlope12                As Double
Dim dSlope13                As Double
Dim dSlope23                As Double

Dim i                       As Long
Dim k                       As Long
Dim lcount                  As Long

With Application.WorksheetFunction

lcount = rX.Rows.Count
If rX.Columns.Count > lcount Then
    lcount = rX.Columns.Count
End If

ReDim dX(1 To lcount) As Double
ReDim dY(1 To lcount) As Double

'read data row-wise or column-wise
If rX.Rows.Count > rX.Columns.Count Then
    For i = 1 To lcount
        dX(i) = rX.Cells(i, 1)
        dY(i) = rY.Cells(i, 1)
    Next i
Else
    For i = 1 To lcount
        dX(i) = rX.Cells(1, i)
        dY(i) = rY.Cells(1, i)
    Next i
End If

ReDim vR(1 To 2, 1 To lcount) As Variant

vR(1, 1) = dX(1)
vR(2, 1) = dY(1)
vR(1, 2) = dX(2)
vR(2, 2) = dY(2)
k = 2
bNewSlope = True
For i = 3 To lcount
    If bNewSlope Then dSlope12 = (vR(2, k) - vR(2, k - 1)) / (vR(1, k) - vR(1, k - 1))
    dSlope13 = (dY(i) - vR(2, k - 1)) / (dX(i) - vR(1, k - 1))
    dSlope23 = (dY(i) - vR(2, k)) / (dX(i) - vR(1, k))
    If Abs(dSlope13 - dSlope12) > dMaxSlopeDelta Or _
        Abs(dSlope13 - dSlope23) > dMaxSlopeDelta Then
        k = k + 1
        bNewSlope = True
    Else
        bNewSlope = False
    End If
    vR(1, k) = dX(i)
    vR(2, k) = dY(i)
Next i
    
ReDim Preserve vR(1 To 2, 1 To k) As Variant

If rX.Rows.Count > rX.Columns.Count Then
    sbReducePoints = .Transpose(vR)
Else
    sbReducePoints = vR
End If

End With

End Function

Please read my Disclaimer.

sbReducePoints.xlsm [192 KB Excel file, open and use at your own risk]